C57BL/6NCrl-Amelxem1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12626
Citation informationRRID:IMSR_EM:12626 

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International strain nameC57BL/6NCrl-Amelxem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolAmelxem1(IMPC)Ccpcz
Gene/Transgene symbolAmelx

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal stomach morphology / IMPC
  • abnormal spleen morphology / IMPC
  • small spleen / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • small seminal vesicle / IMPC
  • decreased body weight / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal tooth morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • vertebral transformation / IMPC
  • enlarged stomach / IMPC
  • abnormal vertebral arch morphology / IMPC
  • increased eosinophil cell number / IMPC
  • decreased lymphocyte cell number / IMPC
  • abnormal zygomatic bone morphology / IMPC
  • increased lung tissue damping / IMPC
  • abnormal tooth color / IMPC
  • absent teeth / IMPC
IMPC phenotypes (gene matching)
  • abnormal thymus morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • abnormal tooth morphology / IMPC
  • abnormal tooth color / IMPC
  • decreased body weight / IMPC
  • increased lung tissue damping / IMPC
  • enlarged thymus / IMPC
  • enlarged stomach / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal stomach morphology / IMPC
  • abnormal spleen morphology / IMPC
  • small spleen / IMPC
  • abnormal vertebral arch morphology / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • increased eosinophil cell number / IMPC
  • absent teeth / IMPC
  • abnormal testis morphology / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal zygomatic bone morphology / IMPC
  • small seminal vesicle / IMPC
  • abnormal skin morphology / IMPC
  • enlarged heart / IMPC
  • decreased lymphocyte cell number / IMPC
  • small testis / IMPC
  • vertebral transformation / IMPC
  • abnormal heart morphology / IMPC

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Register interest

Availabilities

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    Practical information

    Example health report
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    Material Transfer Agreement (MTA)
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