- increased bone mineral density / IMPC
- decreased bone mineral density / IMPC
- decreased circulating HDL cholesterol level / IMPC
- increased mean corpuscular volume / IMPC
- decreased circulating cholesterol level / IMPC
- decreased circulating serum albumin level / IMPC
- increased circulating creatinine level / IMPC
- decreased circulating creatinine level / IMPC
- increased mean corpuscular hemoglobin / IMPC
- increased NK cell number / IMPC
C57BL/6N-Trim8em1(IMPC)Wtsi/WtsiH
Status | Only small colony available |
EMMA ID | EM:12706 |
International strain name | C57BL/6N-Trim8em1(IMPC)Wtsi/WtsiH |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Trim8em1(IMPC)Wtsi |
Gene/Transgene symbol | Trim8 |
Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Early infantile epileptic encephalopathy / Orphanet_1934
IMPC phenotypes (allele matching)
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).