C57BL/6NCrl-Plgem1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12790
Citation informationRRID:IMSR_EM:12790 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Plgem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPlgem1(IMPC)Ccpcz
Gene/Transgene symbolPlg

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • abnormal stomach morphology / MGI
  • abnormal rectum morphology / MGI
  • rectal prolapse / MGI
  • abnormal colon morphology / MGI
  • intestinal ulcer / MGI
  • abnormal liver morphology / MGI
  • abnormal mammary gland development / MGI
  • enlarged lymph nodes / MGI
  • abnormal vagina morphology / MGI
  • abnormal lung morphology / MGI
  • abnormal body weight / MGI
  • decreased body weight / MGI
  • weight loss / MGI
  • abnormal conjunctiva morphology / MGI
  • abnormal cornea morphology / MGI
  • hepatic necrosis / MGI
  • postnatal growth retardation / MGI
  • impaired wound healing / MGI
  • abnormal inflammatory response / MGI
  • eye inflammation / MGI
  • conjunctivitis / MGI
  • abnormal lactation / MGI
  • reduced female fertility / MGI
  • premature death / MGI
  • abnormal larynx morphology / MGI
  • abnormal trachea morphology / MGI
  • abnormal blood coagulation / MGI
  • colitis / MGI
  • enlarged kidney / MGI
  • duodenal ulcer / MGI
  • gastric ulcer / MGI
  • gastrointestinal ulcer / MGI
  • proctitis / MGI
  • liver fibrosis / MGI
  • decreased susceptibility to induced choroidal neovascularization / MGI
  • decreased tumor growth/size / MGI
  • abnormal nervous system physiology / MGI
  • abnormal microglial cell physiology / MGI
  • increased hepatocyte proliferation / MGI
  • abnormal conjunctival epithelium morphology / MGI
  • esophageal ulcer / MGI
  • perianal ulcer / MGI
  • abnormal thrombosis / MGI
  • cachexia / MGI
  • abnormal corneal stroma morphology / MGI
  • cardiovascular system phenotype / MGI
  • corneal vascularization / MGI
  • decreased angiogenesis / MGI
  • abnormal corneal epithelium morphology / MGI
  • pulmonary fibrosis / MGI
  • venoocclusion / MGI
  • ectropion / MGI
  • eye hemorrhage / MGI
  • abnormal mammary gland growth during lactation / MGI
  • abnormal involution of the mammary gland / MGI
  • decreased susceptibility to neuronal excitotoxicity / MGI
  • abnormal mammary gland connective tissue morphology / MGI
  • increased sensitivity to induced morbidity/mortality / MGI
  • decreased sensitivity to induced morbidity/mortality / MGI
  • abnormal acute phase protein level / MGI
  • lactation failure / MGI
  • abnormal kidney thrombosis / MGI
  • increased circulating fibrinogen level / MGI
  • absent corneal epithelium / MGI

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Availabilities

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    Practical information

    Example health report
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    Material Transfer Agreement (MTA)
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