C57BL/6NCrl-Itgb6em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12857
Citation informationRRID:IMSR_EM:12857 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Itgb6em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolItgb6em1(IMPC)Ccpcz
Gene/Transgene symbolItgb6

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • decreased body weight / IMPC
  • anophthalmia / IMPC
  • abnormal skin morphology / IMPC
  • abnormal eye morphology / IMPC
  • abnormal tooth morphology / IMPC
  • abnormal digit morphology / IMPC
  • abnormal inspiratory capacity / IMPC
  • increased circulating alanine transaminase level / IMPC
  • increased circulating creatine kinase level / IMPC
  • decreased respiratory quotient / IMPC
  • increased lung compliance / IMPC
  • decreased lung elastance / IMPC
  • decreased lung tissue damping / IMPC
  • abnormal tooth color / IMPC
  • increased freezing behavior / IMPC
IMPC phenotypes (gene matching)
  • decreased body weight / IMPC
  • decreased lung tissue damping / IMPC
  • abnormal tooth color / IMPC
  • abnormal tooth morphology / IMPC
  • anophthalmia / IMPC
  • enlarged thymus / IMPC
  • decreased lung elastance / IMPC
  • decreased respiratory quotient / IMPC
  • abnormal thymus morphology / IMPC
  • increased circulating alanine transaminase level / IMPC
  • increased freezing behavior / IMPC
  • abnormal digit morphology / IMPC
  • increased lung compliance / IMPC
  • abnormal inspiratory capacity / IMPC
  • increased circulating creatine kinase level / IMPC
  • abnormal eye morphology / IMPC
  • abnormal skin morphology / IMPC

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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