C57BL/6NCrl-Xrcc5em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12867
Citation informationRRID:IMSR_EM:12867 

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International strain nameC57BL/6NCrl-Xrcc5em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolXrcc5em1(IMPC)Ccpcz
Gene/Transgene symbolXrcc5

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal vertebrae morphology / IMPC
  • kyphosis / IMPC
  • scoliosis / IMPC
  • thin ventricular wall / IMPC
  • abnormal cranium morphology / IMPC
  • abnormal spleen morphology / IMPC
  • small spleen / IMPC
  • abnormal thymus morphology / IMPC
  • small thymus / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • abnormal retina morphology / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • decreased exploration in new environment / IMPC
  • increased circulating triglyceride level / IMPC
  • male infertility / IMPC
  • female infertility / IMPC
  • increased mean platelet volume / IMPC
  • abnormal caudal vertebrae morphology / IMPC
  • short tibia / IMPC
  • increased thigmotaxis / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • decreased cardiac output / IMPC
  • increased kidney weight / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • abnormal spine curvature / IMPC
  • abnormal vertebral arch morphology / IMPC
  • abnormal auditory brainstem response / IMPC
  • abnormal zygomatic bone morphology / IMPC
  • decreased circulating serum albumin level / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • increased grip strength / IMPC
  • decreased grip strength / IMPC
  • increased red blood cell distribution width / IMPC
  • abnormal retina blood vessel morphology / IMPC
  • aorta stenosis / IMPC
  • decreased heart left ventricle size / IMPC
  • decreased cardiac stroke volume / IMPC
IMPC phenotypes (gene matching)
  • abnormal retina morphology / IMPC
  • increased thigmotaxis / IMPC
  • increased red blood cell distribution width / IMPC
  • abnormal thymus morphology / IMPC
  • abnormal vertebral arch morphology / IMPC
  • abnormal testis morphology / IMPC
  • increased kidney weight / IMPC
  • abnormal zygomatic bone morphology / IMPC
  • decreased cardiac stroke volume / IMPC
  • decreased circulating serum albumin level / IMPC
  • thin ventricular wall / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal auditory brainstem response / IMPC
  • small spleen / IMPC
  • male infertility / IMPC
  • abnormal vertebrae morphology / IMPC
  • small thymus / IMPC
  • decreased cardiac output / IMPC
  • abnormal spine curvature / IMPC
  • decreased grip strength / IMPC
  • abnormal caudal vertebrae morphology / IMPC
  • aorta stenosis / IMPC
  • increased circulating triglyceride level / IMPC
  • decreased exploration in new environment / IMPC
  • increased mean platelet volume / IMPC
  • short tibia / IMPC
  • female infertility / IMPC
  • small testis / IMPC
  • decreased heart left ventricle size / IMPC
  • abnormal cranium morphology / IMPC
  • hyperactivity / IMPC
  • abnormal retina blood vessel morphology / IMPC
  • increased grip strength / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • scoliosis / IMPC
  • decreased locomotor activity / IMPC
  • kyphosis / IMPC

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

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    Legally binding conditions for the transfer

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