IMPC phenotypes (gene matching)
B6J.129S2-Ncoa6tm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:12924 |
| Citation information | RRID:IMSR_EM:12924 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6J.129S2-Ncoa6tm1.1Ics/Ics |
| Alternative name | RAP-250 CM |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Ncoa6tm1.1Ics |
| Gene/Transgene symbol | Ncoa6 |
Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
| Phenotypic information | Homozygous:NAHeterozygous:NA |
| Breeding history | 10 backcross generations |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal triglyceride level / MGI
- abnormal vascular development / MGI
- abnormal heart morphology / MGI
- abnormal heart development / MGI
- thin ventricular wall / MGI
- trabecula carnea hypoplasia / MGI
- decreased hair follicle number / MGI
- oligodactyly / MGI
- abnormal liver development / MGI
- abnormal liver morphology / MGI
- small liver / MGI
- decreased hepatocyte number / MGI
- abnormal hepatocyte morphology / MGI
- dilated third ventricle / MGI
- abnormal hypothalamus morphology / MGI
- abnormal brain development / MGI
- thick epidermis / MGI
- abnormal lens morphology / MGI
- cataract / MGI
- small lens / MGI
- abnormal eye pigmentation / MGI
- abnormal blood vessel morphology / MGI
- decreased embryo size / MGI
- abnormal placenta morphology / MGI
- abnormal placenta development / MGI
- impaired wound healing / MGI
- delayed brain development / MGI
- reduced male fertility / MGI
- reduced female fertility / MGI
- female infertility / MGI
- decreased litter size / MGI
- abnormal digit morphology / MGI
- abnormal lipid homeostasis / MGI
- disorganized myocardium / MGI
- thin myocardium / MGI
- heart hypoplasia / MGI
- delayed wound healing / MGI
- increased liver weight / MGI
- abnormal epicardium morphology / MGI
- abnormal vitelline vasculature morphology / MGI
- abnormal placenta vasculature / MGI
- abnormal embryonic hematopoiesis / MGI
- absent placental labyrinth / MGI
- absent olfactory bulb / MGI
- abnormal fetal cardiomyocyte proliferation / MGI
- pallor / MGI
- abnormal feces composition / MGI
- increased hepatocyte apoptosis / MGI
- embryonic growth retardation / MGI
- thin myocardium compact layer / MGI
- abnormal spongiotrophoblast layer morphology / MGI
- dilated vasculature / MGI
- abnormal trophoblast layer morphology / MGI
- increased circulating cholesterol level / MGI
- abnormal heart ventricle morphology / MGI
- pericardial effusion / MGI
- abnormal myocardium layer morphology / MGI
- abnormal bile salt homeostasis / MGI
- reproductive system phenotype / MGI
- abnormal cell physiology / MGI
- impaired placental function / MGI
- abnormal fetal cardiomyocyte morphology / MGI
- abnormal placental labyrinth vasculature morphology / MGI
- decreased neuron number / MGI
- abnormal spongiotrophoblast cell morphology / MGI
- decreased erythroid progenitor cell number / MGI
- increased trophoblast giant cell number / MGI
- decreased birth weight / MGI
- decreased birth body size / MGI
- abnormal palatal shelf fusion at midline / MGI
- neonatal lethality, incomplete penetrance / MGI
- embryonic lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- decreased fibroblast proliferation / MGI
- decreased spongiotrophoblast size / MGI
- abnormal liver bud morphology / MGI
- increased sebaceous gland number / MGI
- increased fibroblast apoptosis / MGI
- small thalamus / MGI