B6J.129S2-Nr6a1tm1.2Ics/Ics

Status

Available to order

EMMA IDEM:12985
Citation informationRRID:IMSR_EM:12985 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameB6J.129S2-Nr6a1tm1.2Ics/Ics
Alternative nameGCNF1 KO
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolNr6a1tm1.2Ics
Gene/Transgene symbolNr6a1

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
https://www.mousephenotype.org/data/genes/MGI:1352459

Heterozygous:
https://www.mousephenotype.org/data/genes/MGI:1352459
Breeding history9 backcross generations
ReferencesNone available
Homozygous fertilenot known
Homozygous viableno
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal embryo size / IMPC
  • increased startle reflex / IMPC
  • abnormal tail bud morphology / IMPC
  • abnormal midbrain development / IMPC
  • abnormal hindbrain development / IMPC
  • abnormal chorioallantoic fusion / IMPC
  • abnormal embryo turning / IMPC
  • embryonic growth retardation / IMPC
  • embryonic lethality prior to tooth bud stage / IMPC
  • abnormal heart looping / IMPC
  • pale yolk sac / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • abnormal pericardium morphology / IMPC
  • abnormal forebrain development / IMPC
  • abnormal visceral yolk sac morphology / IMPC
  • abnormal somite shape / IMPC
  • decreased body length / IMPC
  • abnormal neural tube morphology / IMPC
  • abnormal embryo development / IMPC
  • abnormal neural tube closure / IMPC
  • abnormal optic vesicle formation / IMPC
  • abnormal allantois morphology / IMPC
  • abnormal pharyngeal arch morphology / IMPC
  • abnormal heart morphology / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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