B6J;B6NTac-Ppargc1btm1.2Ics/Ics

Status

Available to order

EMMA IDEM:12992
Citation informationRRID:IMSR_EM:12992 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameB6J;B6NTac-Ppargc1btm1.2Ics/Ics
Alternative namePGC1-b KO
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolPpargc1btm1.2Ics
Gene/Transgene symbolPpargc1b

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
not known

Heterozygous:
not known
Breeding history3 backcross generations
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • hypoactivity / MGI
  • increased circulating triglyceride level / MGI
  • increased circulating free fatty acid level / MGI
  • decreased white adipose tissue amount / MGI
  • postnatal lethality / MGI
  • abnormal muscle physiology / MGI
  • hepatic steatosis / MGI
  • decreased circulating triglyceride level / MGI
  • decreased circulating free fatty acid level / MGI
  • abnormal white adipose tissue morphology / MGI
  • abnormal brown adipose tissue morphology / MGI
  • increased liver weight / MGI
  • no phenotypic analysis / MGI
  • decreased circulating cholesterol level / MGI
  • abnormal metabolism / MGI
  • decreased oxygen consumption / MGI
  • decreased triglyceride level / MGI
  • insulin resistance / MGI
  • decreased heart rate / MGI
  • muscle phenotype / MGI
  • adipose tissue phenotype / MGI
  • homeostasis/metabolism phenotype / MGI
  • cardiovascular system phenotype / MGI
  • abnormal mitochondrion morphology / MGI
  • abnormal mitochondrial physiology / MGI
  • decreased survivor rate / MGI
  • abnormal fat cell morphology / MGI
  • increased white fat cell size / MGI
  • decreased gonadal fat pad weight / MGI
  • increased liver triglyceride level / MGI
  • impaired adaptive thermogenesis / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • impaired exercise endurance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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