C57BL/6NCrl-Cd81em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:13052
Citation informationRRID:IMSR_EM:13052 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Cd81em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolCd81em1(IMPC)Ccpcz
Gene/Transgene symbolCd81

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • abnormal microglial cell morphology / MGI
  • abnormal immune system cell morphology / MGI
  • abnormal corpus callosum morphology / MGI
  • thickened cerebral cortex / MGI
  • abnormal hippocampus morphology / MGI
  • abnormal CNS glial cell morphology / MGI
  • hypoactivity / MGI
  • decreased IgG level / MGI
  • increased dopamine level / MGI
  • abnormal B cell differentiation / MGI
  • increased brain weight / MGI
  • abnormal macrophage physiology / MGI
  • increased IgM level / MGI
  • increased IgA level / MGI
  • abnormal neuron morphology / MGI
  • nervous system phenotype / MGI
  • abnormal nucleus accumbens morphology / MGI
  • abnormal B cell morphology / MGI
  • decreased B-1 B cell number / MGI
  • decreased susceptibility to parasitic infection / MGI
  • decreased B cell proliferation / MGI
  • abnormal T cell proliferation / MGI
  • increased B cell proliferation / MGI
  • abnormal T-helper 2 physiology / MGI
  • decreased susceptibility to type I hypersensitivity reaction / MGI
  • decreased B-1a cell number / MGI
  • abnormal hippocampus CA1 region morphology / MGI
  • decreased IgG1 level / MGI
  • increased IgG3 level / MGI
  • impaired behavioral response to cocaine / MGI
  • abnormal hippocampus pyramidal cell morphology / MGI
  • increased astrocyte number / MGI
  • increased hippocampus volume / MGI

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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