C57BL/6NCrl-Psmb11em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:13113
Citation informationRRID:IMSR_EM:13113 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Psmb11em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPsmb11em1(IMPC)Ccpcz
Gene/Transgene symbolPsmb11

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal colon morphology / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • abnormal skin morphology / IMPC
  • abnormal digit morphology / IMPC
  • abnormal ileum morphology / IMPC
  • increased kidney weight / IMPC
  • increased NK T cell number / IMPC
  • increased CD4-positive, alpha-beta T cell number / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • increased CD4-positive NK T cell number / IMPC
  • increased memory-marker CD4-positive NK T cell number / IMPC
  • increased T-helper cell number / IMPC
  • decreased effector memory T-helper cell number / IMPC
  • increased effector memory T-helper cell number / IMPC
IMPC phenotypes (gene matching)
  • increased T-helper cell number / IMPC
  • increased effector memory T-helper cell number / IMPC
  • increased NK T cell number / IMPC
  • abnormal skin morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal colon morphology / IMPC
  • increased CD4-positive NK T cell number / IMPC
  • abnormal thymus morphology / IMPC
  • small testis / IMPC
  • increased CD4-positive, alpha-beta T cell number / IMPC
  • increased memory-marker CD4-positive NK T cell number / IMPC
  • enlarged thymus / IMPC
  • abnormal digit morphology / IMPC
  • abnormal spleen morphology / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • increased kidney weight / IMPC
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal testis morphology / IMPC
  • decreased effector memory T-helper cell number / IMPC
  • abnormal ileum morphology / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

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