STOCK Loxl3tm1a(EUCOMM)Wtsi/Cnbc
| Status | Available to order |
| EMMA ID | EM:13124 |
| International strain name | STOCK Loxl3tm1a(EUCOMM)Wtsi/Cnbc |
| Alternative name | APC |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Loxl3tm1a(EUCOMM)Wtsi, |
| Gene/Transgene symbol | Loxl3 |
Information from provider
| Provider | Francisco Portillo |
| Provider affiliation | Biochemistry, Universidad Autonoma de Madrid |
| Additional owner | Amparo Cano and Patricia G Santamaria, Universidad Autónoma de Madrid, Madrid, Spain |
| Genetic information | Targeted mutation in the Loxl3 gene. ES cell clones containing a targeted mutation of Loxl3 (Loxl3tm1a(EUCOMM)Wtsi, conditional ready, null/knockout, reporter - cre recombinase/loxP system) were obtained from the EUCOMM repository. |
| Phenotypic information | Homozygous:Partial perinatal lethality due to osteo-articular defects.Heterozygous:None |
| Breeding history | ES clones cells containing a targeted mutation of Loxl3 (Loxl3tm1a(EUCOMM)Wtsi, conditional ready, null/knockout, reporter - cre recombinase/loxP system) were obtained from the EUCOMM repository. Heterozygous animals were intercrossed to obtain homozygous animals. |
| References | None available |
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous mixed |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive Stickler syndrome / Orphanet_250984