B6;CBA-Tg(Sf1-Hoxb9)52Aswn/H
| Status | Available to order |
| EMMA ID | EM:13203 |
| Citation information | RRID:IMSR_EM:13203 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;CBA-Tg(Sf1-Hoxb9)52Aswn/H |
| Alternative name | Sf1- Hoxb9 (BAC52) |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Sf1-Hoxb9)52Aswn |
| Gene/Transgene symbol | Tg(Sf1-Hoxb9)52Aswn |
Information from provider
| Provider | Amanda Swain |
| Provider affiliation | Institute of Cancer Research |
| Genetic information | Mouse BAC transgene containing Sf1 locus with mouse Hoxb9 gene cDNA, plus rabbit beta globin polyadenylation inserted in the 5' untranslated region. |
| Phenotypic information | Homozygous:Homozygous animals have not been characterised.Heterozygous:Transgenic adrenals have a larger X zone |
| Breeding history | Crossed to either non-transgenic littermates or C57BL/6. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours.;Francis Jeffrey C, Gardiner Jennifer R, Renaud Yoan, Chauhan Ritika, Weinstein Yacob, Gomez-Sanchez Celso, Lefrançois-Martinez Anne-Marie, Bertherat Jérôme, Val Pierre, Swain Amanda, ;2021;British journal of cancer;124;805-816; 33214683