C57BL/6NTac-Btktm1c(EUCOMM)Hmgu/IcsOrl
Status | Available to order |
EMMA ID | EM:13217 |
International strain name | C57BL/6NTac-Btktm1c(EUCOMM)Hmgu/IcsOrl |
Alternative name | C57BL/6NTac-Btk |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Btktm1c(EUCOMM)Hmgu, |
Gene/Transgene symbol | Btk |
Information from provider
Provider | Cécile FREMOND |
Provider affiliation | CNRS-TAAM-UAR44 |
Genetic information | This mouse line originates from EUCOMM ES clone HEPD0522_1_A11. For further details on the construction of this clone see the page at the IMPC portal. The tm1a mice have been crossed with flp recombinase-expressing mice (EM:05490, C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics) to obtain the tm1c allele. |
Phenotypic information | Homozygous:Homozygous mice have not been generatedHeterozygous:Null |
Breeding history | Rederived tm1a mice have been crossed with flp recombinase-expressing mice to obtain the tm1c allele. |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Animals used for archiving | heterozygous C57BL/6N Tac |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia / Orphanet_632
- X-linked agammaglobulinemia / Orphanet_47
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