- increased bone mineral density / IMPC
- increased leukocyte cell number / IMPC
- increased neutrophil cell number / IMPC
- increased monocyte cell number / IMPC
- tremors / IMPC
- hyperactivity / IMPC
- abnormal gait / IMPC
- decreased startle reflex / IMPC
- increased basophil cell number / IMPC
- increased heart rate / IMPC
- short tibia / IMPC
- increased circulating alanine transaminase level / IMPC
- increased circulating alkaline phosphatase level / IMPC
- increased spleen weight / IMPC
- increased lymphocyte cell number / IMPC
- decreased lymphocyte cell number / IMPC
- increased circulating aspartate transaminase level / IMPC
- decreased circulating serum albumin level / IMPC
- decreased circulating glucose level / IMPC
- increased circulating amylase level / IMPC
- increased circulating iron level / IMPC
- decreased prepulse inhibition / IMPC
- increased red blood cell distribution width / IMPC
- increased large unstained cell number / IMPC
C57BL/6NTac-Epg5em1(IMPC)H/H
Status | Available to order |
EMMA ID | EM:13286 |
Citation information | RRID:IMSR_EM:13286 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NTac-Epg5em1(IMPC)H/H |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Epg5em1(IMPC)H |
Gene/Transgene symbol | Epg5 |
Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Vici syndrome / Orphanet_1493
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- decreased prepulse inhibition / IMPC
- increased heart rate / IMPC
- decreased lymphocyte cell number / IMPC
- increased spleen weight / IMPC
- decreased startle reflex / IMPC
- increased large unstained cell number / IMPC
- increased red blood cell distribution width / IMPC
- increased neutrophil cell number / IMPC
- tremors / IMPC
- increased circulating aspartate transaminase level / IMPC
- increased circulating amylase level / IMPC
- increased lymphocyte cell number / IMPC
- hyperactivity / IMPC
- increased circulating alanine transaminase level / IMPC
- short tibia / IMPC
- increased monocyte cell number / IMPC
- increased circulating alkaline phosphatase level / IMPC
- increased basophil cell number / IMPC
- increased leukocyte cell number / IMPC
- abnormal gait / IMPC
- increased circulating iron level / IMPC
- decreased circulating glucose level / IMPC
- increased bone mineral density / IMPC
- decreased circulating serum albumin level / IMPC
Information on how we integrate external resources can be found here
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).