IMPC phenotypes (allele matching)
C57BL/6NTac-Park7em1(IMPC)H/H
| Status | Available to order |
| EMMA ID | EM:13335 |
| Citation information | RRID:IMSR_EM:13335 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NTac-Park7em1(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Park7em1(IMPC)H |
| Gene/Transgene symbol | Park7 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Young-onset Parkinson disease / Orphanet_2828
MGI phenotypes (gene matching)
- weight loss / MGI
- abnormal stationary movement / MGI
- hypoactivity / MGI
- impaired coordination / MGI
- abnormal gait / MGI
- short stride length / MGI
- abnormal motor coordination/balance / MGI
- impaired limb coordination / MGI
- absent long term depression / MGI
- abnormal dopamine level / MGI
- increased dopamine level / MGI
- abnormal motor capabilities/coordination/movement / MGI
- decreased vertical activity / MGI
- abnormal motor learning / MGI
- neuron degeneration / MGI
- loss of dopaminergic neurons / MGI
- abnormal locomotor activation / MGI
- abnormal neurotransmitter uptake / MGI
- nervous system phenotype / MGI
- abnormal locus ceruleus morphology / MGI
- abnormal striatum morphology / MGI
- bradykinesia / MGI
- behavior/neurological phenotype / MGI
- abnormal action potential / MGI
- abnormal physiological response to xenobiotic / MGI
- abnormal behavioral response to xenobiotic / MGI
- decreased grip strength / MGI
- abnormal cellular respiration / MGI
- abnormal tricarboxylic acid cycle / MGI
- increased susceptibility to dopaminergic neuron neurotoxicity / MGI
- abnormal substantia nigra pars compacta morphology / MGI