C57BL/6NCrl-Gria1em1(IMPC)Hmgu/Ieg
Status | Available to order |
EMMA ID | EM:13442 |
Citation information | RRID:IMSR_EM:13442 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Gria1em1(IMPC)Hmgu/Ieg |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Gria1em1(IMPC)Hmgu |
Gene/Transgene symbol | Gria1 |
Information from provider
Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6N males |
Disease and phenotype information
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- hyperactivity / IMPC
- increased circulating amylase level / IMPC
- decreased freezing behavior / IMPC
- decreased exploration in new environment / IMPC
- increased circulating serum albumin level / IMPC
- decreased prepulse inhibition / IMPC
- increased blood urea nitrogen level / IMPC
- impaired contextual conditioning behavior / IMPC
- increased circulating alkaline phosphatase level / IMPC
- abnormal freezing behavior / IMPC
- abnormal gait / IMPC
- impaired cued conditioning behavior / IMPC
- increased circulating iron level / IMPC
- increased mechanical nociceptive threshold / IMPC
- abnormal locomotor behavior / IMPC
- decreased bone mineral content / IMPC
- decreased vertical activity / IMPC
- hypoalgesia / IMPC
- decreased startle reflex / IMPC
MGI phenotypes (gene matching)
- abnormal spinal cord morphology / MGI
- decreased body size / MGI
- abnormal social investigation / MGI
- increased anxiety-related response / MGI
- decreased anxiety-related response / MGI
- abnormal locomotor behavior / MGI
- hyperactivity / MGI
- abnormal response to new environment / MGI
- increased exploration in new environment / MGI
- reduced long term potentiation / MGI
- absent long term depression / MGI
- impaired synaptic plasticity / MGI
- abnormal associative learning / MGI
- no abnormal phenotype detected / MGI
- abnormal long term potentiation / MGI
- abnormal sexual interaction / MGI
- abnormal emotion/affect behavior / MGI
- increased vertical activity / MGI
- abnormal nociception after inflammation / MGI
- no phenotypic analysis / MGI
- nervous system phenotype / MGI
- decreased aggression towards males / MGI
- abnormal serotonin level / MGI
- homeostasis/metabolism phenotype / MGI
- behavior/neurological phenotype / MGI
- increased blood urea nitrogen level / MGI
- decreased glycosylated hemoglobin level / MGI
- abnormal dendrite morphology / MGI
- abnormal long term spatial reference memory / MGI
- decreased chemical nociceptive threshold / MGI
- induced hyperactivity / MGI
- abnormal behavioral response to xenobiotic / MGI
- decreased behavioral withdrawal response / MGI
- reduced AMPA-mediated synaptic currents / MGI
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