B6;129P2-Tg(Flt4)1Bld/Cnrm
| Status | Available to order |
| EMMA ID | EM:13465 |
| International strain name | B6;129P2-Tg(Flt4)1Bld/Cnrm |
| Alternative name | TgVegfr3 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Flt4)1Bld |
| Gene/Transgene symbol | Tg(Flt4)1Bld |
Information from provider
| Provider | Antonio Baldini |
| Provider affiliation | Istituto di genetica e biofisica |
| Genetic information | The transgenic mouse line carries a single copy of a transgene containing a full length cDNA of the mouse Flt4 (FMS-like tyrosine kinase 4; or Vegfr3, vascular endothelial cell growth factor receptor 3) wild-type gene, generated by transfection of the transgene into mouse embryonic stem cells (ESC; E14Tg2A.4), followed by microinjection of the mESC into mouse blastocysts. |
| Phenotypic information | Homozygous:not generatedHeterozygous:none |
| Breeding history | Intercrossed with C57BL/6 and in sib-matings. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- A dual role for Tbx1 in cardiac lymphangiogenesis through genetic interaction with Vegfr3.;Martucciello Stefania, Turturo Maria Giuseppina, Bilio Marchesa, Cioffi Sara, Chen Li, Baldini Antonio, Illingworth Elizabeth, ;2020;FASEB journal : official publication of the Federation of American Societies for Experimental Biology;34;15062-15079; 32951265