- hyperactivity / IMPC
- decreased locomotor activity / IMPC
- decreased exploration in new environment / IMPC
- abnormal seminal vesicle morphology / IMPC
- increased hematocrit / IMPC
- decreased vertical activity / IMPC
- decreased lean body mass / IMPC
- increased total body fat amount / IMPC
- decreased bone mineral content / IMPC
- decreased respiratory quotient / IMPC
- decreased food intake / IMPC
C57BL/6NCrl-Ube3aem1(IMPC)Hmgu/Ieg
Status | Available to order |
EMMA ID | EM:13473 |
Citation information | RRID:IMSR_EM:13473 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Ube3aem1(IMPC)Hmgu/Ieg |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Ube3aem1(IMPC)Hmgu |
Gene/Transgene symbol | Ube3a |
Information from provider
Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6N males |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Angelman syndrome due to a point mutation / Orphanet_411511
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- hyperactivity / IMPC
- decreased locomotor activity / IMPC
- decreased vertical activity / IMPC
- decreased exploration in new environment / IMPC
- decreased lean body mass / IMPC
- increased total body fat amount / IMPC
- increased hematocrit / IMPC
- decreased food intake / IMPC
- decreased respiratory quotient / IMPC
- decreased bone mineral content / IMPC
- abnormal seminal vesicle morphology / IMPC
Information on how we integrate external resources can be found here
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