C57BL/6NCrl-Neurod2em1(IMPC)Hmgu/Ieg

Status

Available to order

EMMA IDEM:13481
Citation informationRRID:IMSR_EM:13481 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Neurod2em1(IMPC)Hmgu/Ieg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolNeurod2em1(IMPC)Hmgu
Gene/Transgene symbolNeurod2

Information from provider

Provider Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N males

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • decreased circulating calcium level / IMPC
  • abnormal lens morphology / IMPC
  • cataract / IMPC
  • abnormal cornea morphology / IMPC
  • corneal opacity / IMPC
  • abnormal retina morphology / IMPC
  • increased anxiety-related response / IMPC
  • abnormal locomotor behavior / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • increased exploration in new environment / IMPC
  • decreased startle reflex / IMPC
  • abnormal coat appearance / IMPC
  • decreased vertical activity / IMPC
  • short tibia / IMPC
  • increased thigmotaxis / IMPC
  • abnormal behavior / IMPC
  • narrow eye opening / IMPC
  • corneal deposits / IMPC
  • decreased prepulse inhibition / IMPC
  • increased total body fat amount / IMPC
  • increased grip strength / IMPC
  • decreased respiratory quotient / IMPC
  • decreased food intake / IMPC
IMPC phenotypes (gene matching)
  • hyperactivity / IMPC
  • increased anxiety-related response / IMPC
  • narrow eye opening / IMPC
  • decreased startle reflex / IMPC
  • cataract / IMPC
  • decreased circulating calcium level / IMPC
  • decreased locomotor activity / IMPC
  • increased exploration in new environment / IMPC
  • abnormal lens morphology / IMPC
  • abnormal coat appearance / IMPC
  • abnormal locomotor behavior / IMPC
  • short tibia / IMPC
  • abnormal behavior / IMPC
  • increased thigmotaxis / IMPC
  • abnormal cornea morphology / IMPC
  • abnormal retina morphology / IMPC
  • decreased prepulse inhibition / IMPC
  • decreased respiratory quotient / IMPC
  • increased total body fat amount / IMPC
  • decreased food intake / IMPC
  • corneal opacity / IMPC
  • decreased vertical activity / IMPC
  • corneal deposits / IMPC
  • increased grip strength / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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