IMPC phenotypes (allele matching)
- increased circulating lipase level / IMPC
C57BL/6NCrl-Oma1em1(IMPC)Hmgu/Ieg
| Status | Available to order |
| EMMA ID | EM:13507 |
| Citation information | RRID:IMSR_EM:13507 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NCrl-Oma1em1(IMPC)Hmgu/Ieg |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Oma1em1(IMPC)Hmgu |
| Gene/Transgene symbol | Oma1 |
Information from provider
| Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References |
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Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6N males |
Disease and phenotype information
IMPC phenotypes (gene matching)
- increased circulating lipase level / IMPC
Literature references
- Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy.;Ahola Sofia, Pazurek Lilli A, Mayer Fiona, Lampe Philipp, Hermans Steffen, Becker Lore, Amarie Oana V, Fuchs Helmut, Gailus-Durner Valerie, de Angelis Martin Hrabe, Riedel Dietmar, Nolte Hendrik, Langer Thomas, ;2024;Science advances;10;eadp0443; 39093974