- decreased bone mineral density / IMPC
- increased circulating LDL cholesterol level / IMPC
- decreased circulating calcium level / IMPC
- decreased hematocrit / IMPC
- increased mean corpuscular volume / IMPC
- increased mean platelet volume / IMPC
- decreased hemoglobin content / IMPC
- decreased erythrocyte cell number / IMPC
- abnormal bone structure / IMPC
- decreased lean body mass / IMPC
- increased B cell number / IMPC
- decreased T cell number / IMPC
- impaired glucose tolerance / IMPC
- decreased circulating thyroxine level / IMPC
- decreased circulating total protein level / IMPC
- increased circulating potassium level / IMPC
- decreased CD4-positive, alpha beta T cell number / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
- decreased total body fat amount / IMPC
- decreased grip strength / IMPC
- increased circulating magnesium level / IMPC
- abnormal incisor color / IMPC
- decreased bone mineral content / IMPC
B6Dnk;B6Brd;B6N-Tyrc-Brd Tmem189tm1a(KOMP)Wtsi/WtsiOrl
Status | Available to order |
EMMA ID | EM:13673 |
International strain name | B6Dnk;B6Brd;B6N-Tyrc-Brd Tmem189tm1a(KOMP)Wtsi/WtsiOrl |
Alternative name | EPD0026_4_C08 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Tmem189tm1a(KOMP)Wtsi, |
Gene/Transgene symbol | Tmem189 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from KOMP ES clone EPD0026_4_C08. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Animals used for archiving | heterozygous B6Brd;B6Dnk;B6N-Tyr |
Disease and phenotype information
IMPC phenotypes (allele matching)
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