C57BL/6N-Prdm8em1(IMPC)Wtsi/WtsiCnbc

Status

Available to order

EMMA IDEM:13886
Citation informationRRID:IMSR_EM:13886 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6N-Prdm8em1(IMPC)Wtsi/WtsiCnbc
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPrdm8em1(IMPC)Wtsi
Gene/Transgene symbolPrdm8

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous C57BL/6N males

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • abnormal spleen morphology / IMPC
  • small spleen / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal uterus morphology / IMPC
  • decreased body weight / IMPC
  • abnormal retina morphology / IMPC
  • increased anxiety-related response / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal tooth morphology / IMPC
  • small heart / IMPC
  • abnormal inspiratory capacity / IMPC
  • increased heart rate / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • enlarged uterus / IMPC
  • impaired glucose tolerance / IMPC
  • increased circulating sodium level / IMPC
  • increased prepulse inhibition / IMPC
  • increased airway resistance / IMPC
  • increased lung elastance / IMPC
  • increased freezing behavior / IMPC
IMPC phenotypes (gene matching)
  • increased heart rate / IMPC
  • increased circulating sodium level / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal retina morphology / IMPC
  • hyperactivity / IMPC
  • impaired glucose tolerance / IMPC
  • decreased locomotor activity / IMPC
  • abnormal tooth morphology / IMPC
  • decreased body weight / IMPC
  • increased prepulse inhibition / IMPC
  • increased freezing behavior / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • increased airway resistance / IMPC
  • small heart / IMPC
  • small spleen / IMPC
  • abnormal inspiratory capacity / IMPC
  • abnormal uterus morphology / IMPC
  • abnormal heart morphology / IMPC
  • increased anxiety-related response / IMPC
  • enlarged uterus / IMPC
  • increased lung elastance / IMPC
MGI phenotypes (gene matching)
  • skin lesions / MGI
  • excessive scratching / MGI
  • abnormal motor coordination/balance / MGI
  • absent corpus callosum / MGI
  • abnormal axon guidance / MGI
  • nervous system phenotype / MGI
  • absent hippocampal commissure / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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