B6.129-Ntn1Gt(IRESBetageo)1Pgr/Cnrm
Status | Available to order |
EMMA ID | EM:00139 |
International strain name | B6.129-Ntn1Gt(IRESBetageo)1Pgr/Cnrm |
Alternative name | Ntn1-gt |
Strain type | Gene-trap |
Allele/Transgene symbol | Ntn1Gt(IRESBetageo)1Pgr, |
Gene/Transgene symbol | Ntn1 |
Information from provider
Provider | Peter Gruss |
Provider affiliation | Max Planck Inst. Biophysical Chemistry |
Genetic information | Insertion of the IRES-geo vector into the netrin 1 locus. |
Phenotypic information | Mutants lack two inner ear semicircular canals. |
Breeding history | Backcrossed to C57BL/6 (more than 7 backcross generations). |
References |
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Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Familial congenital mirror movements / Orphanet_238722
MGI phenotypes (allele matching)
Literature references
- Netrin 1 is required for semicircular canal formation in the mouse inner ear.;Salminen M, Meyer B I, Bober E, Gruss P, ;2000;Development (Cambridge, England);127;13-22; 10654596
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