MGI phenotypes (allele matching)
- abnormal glucose homeostasis / MGI
NOD.B6-(D1Mit302-D1Mit178)/GhjCnrm
| Status | Available to order |
| EMMA ID | EM:01392 |
| International strain name | NOD.B6-(D1Mit302-D1Mit178)/GhjCnrm |
| Alternative name | NOD.B6-Idd5-R39 |
| Strain type | Other |
| Allele/Transgene symbol | Idd5.1C57BL/6J, |
| Gene/Transgene symbol | Idd5.1 |
Information from provider
| Provider | Henri-Jean Garchon |
| Provider affiliation | ER70 CNRS et Unite 125 Inserm |
| Genetic information | NOD congenic strain with a proximal segment of chromosome 1 from C57BL/6 surrounding the Idd5 locus. |
| Phenotypic information | This strain is strongly protected against type 1 diabetes. |
| Breeding history | 20 generations of backcrosses. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Further mapping of the Idd5.1 locus for autoimmune diabetes in NOD mice.;Lamhamedi-Cherradi S E, Boulard O, Gonzalez C, Kassis N, Damotte D, Eloy L, Fluteau G, Lévi-Strauss M, Garchon H J, ;2001;Diabetes;50;2874-8; 11723074
- NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.;Hill N J, Lyons P A, Armitage N, Todd J A, Wicker L S, Peterson L B, ;2000;Diabetes;49;1744-7; 11016460