NOD.B6-Idd5^C57BL/6(R33)/GhjOrl

Status	Available to order
EMMA ID	EM:01413
International strain name	NOD.B6-Idd5^C57BL/6(R33)/GhjOrl
Alternative name	NOD.B6-Idd5-R33
Strain type	Spontaneous
Allele/Transgene symbol	Ctla4
Gene/Transgene symbol	Ctla4

Information from provider

Provider	Henri-Jean Garchon
Provider affiliation	ER70 CNRS et Unite 125 Inserm
Genetic information	NOD congenic strain with a proximal segment of chromosome 1 from C57BL/6 surrounding the Idd5 locus.
Phenotypic information	This strain is NOT significantly protected against type 1 diabetes, despite having the Ctla4 gene of the B6 type.
Breeding history	20 generations of backcrosses.
References	None available

Information from EMMA

Archiving centre	Institut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency / Orphanet_436159

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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NOD.B6-Idd5C57BL/6(R33)/GhjOrl