C57BL/6N-Ap4m1tm1b(EUCOMM)Wtsi/WtsiOrl
Status | Available to order |
EMMA ID | EM:14216 |
International strain name | C57BL/6N-Ap4m1tm1b(EUCOMM)Wtsi/WtsiOrl |
Alternative name | EPD0808_1_D06 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Ap4m1tm1b(EUCOMM)Wtsi, |
Gene/Transgene symbol | Ap4m1 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0808_1_D06. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele using a cell permeable HTN-Cre as described in doi:10.1007/s11248-013-9764-x. Click here for more information on EUCOMM final vectors. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Severe intellectual disability and progressive spastic paraplegia / Orphanet_280763
IMPC phenotypes (allele matching)
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