- increased bone mineral density / IMPC
- increased mean corpuscular volume / IMPC
- decreased circulating glycerol level / IMPC
- increased lean body mass / IMPC
- increased B cell number / IMPC
- decreased T cell number / IMPC
- increased mean corpuscular hemoglobin / IMPC
- decreased CD4-positive, alpha beta T cell number / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
- decreased total body fat amount / IMPC
- increased bone mineral content / IMPC
- decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number / IMPC
- decreased effector memory CD8-positive, alpha-beta T cell number / IMPC
- decreased alpha-beta T cell number / IMPC
- decreased Ly6C low monocyte number / IMPC
- decreased fasted circulating glucose level / IMPC
- increased fasted circulating glucose level / IMPC
C57BL/6N-Bhlhe40tm1b(KOMP)Wtsi/WtsiOrl
Status | Available to order |
EMMA ID | EM:14413 |
International strain name | C57BL/6N-Bhlhe40tm1b(KOMP)Wtsi/WtsiOrl |
Alternative name | EPD0208_6_A02 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Bhlhe40tm1b(KOMP)Wtsi |
Gene/Transgene symbol | Bhlhe40 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from KOMP ES clone EPD0208_6_A02. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele using a cell permeable HTN-Cre as described in doi:10.1007/s11248-013-9764-x. Click here for more information on KOMP final vectors. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
IMPC phenotypes (allele matching)
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