IMPC phenotypes (allele matching)
C57BL/6N-Phf8em2(IMPC)Wtsi/WtsiCnbc
| Status | Available to order |
| EMMA ID | EM:14446 |
| Citation information | RRID:IMSR_EM:14446 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Phf8em2(IMPC)Wtsi/WtsiCnbc |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Phf8em2(IMPC)Wtsi |
| Gene/Transgene symbol | Phf8 |
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6N males |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- X-linked intellectual disability, Siderius type / Orphanet_85287
IMPC phenotypes (gene matching)
- improved glucose tolerance / IMPC
- abnormal eye anterior chamber depth / IMPC
- decreased erythrocyte cell number / IMPC
- abnormal heart left ventricle morphology / IMPC
- increased circulating HDL cholesterol level / IMPC
- decreased lymphocyte cell number / IMPC
- increased mean corpuscular hemoglobin / IMPC
- increased circulating cholesterol level / IMPC
- increased circulating alanine transaminase level / IMPC
- increased circulating LDL cholesterol level / IMPC
- increased neutrophil cell number / IMPC