IMPC phenotypes (allele matching)
C57BL/6N-Sh3pxd2atm1b(EUCOMM)Wtsi/WtsiCnbc
| Status | Available to order |
| EMMA ID | EM:14517 |
| International strain name | C57BL/6N-Sh3pxd2atm1b(EUCOMM)Wtsi/WtsiCnbc |
| Alternative name | EPD0656_1_B12 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Sh3pxd2atm1b(EUCOMM)Wtsi, |
| Gene/Transgene symbol | Sh3pxd2a |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0656_1_B12. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele using a cell permeable HTN-Cre as described in doi:10.1007/s11248-013-9764-x. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
MGI phenotypes (allele matching)
- abnormal basioccipital bone morphology / MGI
- abnormal vertebral body morphology / MGI
- abnormal interatrial septum morphology / MGI
- double outlet right ventricle / MGI
- abnormal atrioventricular cushion morphology / MGI
- short snout / MGI
- abnormal liver morphology / MGI
- liver hypoplasia / MGI
- enlarged liver sinusoidal spaces / MGI
- abnormal pineal gland morphology / MGI
- abnormal forebrain morphology / MGI
- fused dorsal root ganglion / MGI
- small superior cervical ganglion / MGI
- abnormal testis morphology / MGI
- abnormal lymphatic vessel morphology / MGI
- abnormal muscle morphology / MGI
- abnormal kidney morphology / MGI
- abnormal brain morphology / MGI
- abnormal artery morphology / MGI
- abnormal nasal cavity morphology / MGI
- abnormal nasal septum morphology / MGI
- abnormal vomeronasal organ morphology / MGI
- abnormal larynx morphology / MGI
- persistent truncus arteriosis / MGI
- abnormal semilunar valve morphology / MGI
- small thyroid gland / MGI
- dilated bile duct / MGI
- bifid ureter / MGI
- urinary bladder hypoplasia / MGI
- abnormal eye muscle morphology / MGI
- abnormal Mullerian duct morphology / MGI
- diaphragmatic hernia / MGI
- transposition of great arteries / MGI
- abnormal adenohypophysis morphology / MGI
- fetal growth retardation / MGI
- abnormal optic cup morphology / MGI
- basisphenoid bone foramen / MGI
- abnormal vertebral arch morphology / MGI
- fusion of vertebral arches / MGI
- absent stapedial artery / MGI
- abnormal occipital bone morphology / MGI
- abnormal inferior vena cava morphology / MGI
- abnormal heart position or orientation / MGI
- absent styloid process / MGI
- enlarged fourth ventricle / MGI
- enlarged third ventricle / MGI
- abnormal cervical rib / MGI
- thoracoschisis / MGI
- absent sublingual gland / MGI
- abnormal right lung morphology / MGI
- abnormal liver vasculature morphology / MGI
- abnormal hyoid bone body morphology / MGI
- atrial septal defect / MGI
- ostium primum atrial septal defect / MGI
- perimembraneous ventricular septal defect / MGI
- muscular ventricular septal defect / MGI
- double inlet heart left ventricle / MGI
- abnormal hepatic vein morphology / MGI
- bicuspid aortic valve / MGI
- abnormal pectinate muscle morphology / MGI
- bicuspid pulmonary valve / MGI
- cerebral arteriovenous malformation / MGI
- persistent right dorsal aorta / MGI
- abnormal aortic valve cusp morphology / MGI
- abnormal pulmonary valve cusp morphology / MGI
- fusion of atlas and occipital bones / MGI
- abnormal lung position or orientation / MGI
- herniated liver / MGI
- pelvic kidney / MGI
- double ureter / MGI
- double outlet right ventricle with atrioventricular septal defect / MGI
- dual inferior vena cava / MGI
- abnormal basilar artery morphology / MGI
- abnormal oral cavity morphology / MGI
- absent hypoglossal canal / MGI
- absent hypoglossal nerve / MGI
- abnormal hypoglossal nerve topology / MGI
- absent segment of posterior cerebral artery / MGI
- abnormal eye muscle topology / MGI
- retropharyngeal edema / MGI
- retropleural edema / MGI
- subcutaneous edema / MGI
- abnormal Mullerian duct topology / MGI
- absent celiac artery / MGI
- abnormal stapedial artery topology / MGI
- absent ductus venosus valve / MGI
- abnormal ductus venosus valve topology / MGI
- persistent right 6th pharyngeal arch artery / MGI
- small prevertebral sympathetic ganglia / MGI
- abnormal vascular plexus formation / MGI
- abnormal digastric muscle connection / MGI
- abnormal olfactory bulb position / MGI
- fragmented Meckel's cartilage / MGI
- abnormal thymus topology / MGI
- fusion of axis and occipital bones / MGI
- abnormally deep median sulcus of tongue / MGI
- abnormal infrahyoid muscle connection / MGI
- reduced sympathetic cervical ganglion size / MGI
- absent connection between subcutaneous lymph vessels and lymph sac / MGI
- blood in lymph vessels / MGI
- abnormal left vena cava superior connection / MGI
- symmetric azygos veins / MGI
- inverse situs of great intrathoracic arteries / MGI
- abnormal vitelline vein topology / MGI
- abnormal vertebral artery origin / MGI
- absent canalicular internal carotid artery segment / MGI
- absent parasellar internal carotid artery / MGI
- abnormal ovary tissue architecture / MGI
- abnormal Wolffian duct connection / MGI
- embryo cyst / MGI
- heterochrony / MGI
- short tongue / MGI