C57BL/6J-Zik1em1Imb/Imb
| Status | Available to order |
| EMMA ID | EM:14668 |
| Citation information | RRID:IMSR_EM:14668 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Zik1em1Imb/Imb |
| Alternative name | Zik1 |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Zik1 |
| Gene/Transgene symbol | Zik1 |
Information from provider
| Provider | Michael Imbeault |
| Provider affiliation | Genetics, University of Cambridge |
| Genetic information | Knock-out of the Zik1 Krüppel-associated box (KRAB) zinc finger protein (ZFP), using CRISPR. C57BL/6 embryos were electroporated followed by implantation. CRISPR technology details: the TrueCut Cas9 protein was micro-injected/electroporated, so no Cas9 gene was inserted into the genome. |
| Phenotypic information | Homozygous:No noticeable phenotype.Heterozygous:No noticeable phenotype. |
| Breeding history | 2 crosses of heterozygotes with wild-type C57BL/6 mice, and 2 het/het sib matings. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |