C57BL/6NTac-Hoxb4^em1(IMPC)H/H

Status	Available to order
EMMA ID	EM:14757
Citation information	RRID:IMSR_EM:14757 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C57BL/6NTac-Hoxb4^em1(IMPC)H/H
Alternative name
Strain type	Endonuclease-mediated
Allele/Transgene symbol	Hoxb4^em1(IMPC)H
Gene/Transgene symbol	Hoxb4

Information from provider

Provider	MRC, Medical Research Council
Provider affiliation	Mary Lyon Centre at MRC Harwell
Genetic information	This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic information	Potential phenotyping data in the IMPC portal
References	None available

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)

abnormal sternum morphology / MGI
abnormal heart morphology / MGI
thin ventricular wall / MGI
decreased bone marrow cell number / MGI
spleen hypoplasia / MGI
decreased body size / MGI
edema / MGI
respiratory distress / MGI
abnormal definitive hematopoiesis / MGI
no abnormal phenotype detected / MGI
decreased hemoglobin content / MGI
decreased erythrocyte cell number / MGI
abnormal cervical vertebrae morphology / MGI
abnormal abdominal wall morphology / MGI
abnormal ventral body wall morphology / MGI
abnormal body wall morphology / MGI
absent pericardium / MGI
pallor / MGI
diaphragmatic hernia / MGI
abnormal chest morphology / MGI
split sternum / MGI
abnormal sternebra morphology / MGI
abnormal cervical axis morphology / MGI
cervical vertebral transformation / MGI
muscle phenotype / MGI
growth/size/body region phenotype / MGI
skeleton phenotype / MGI
abnormal heart position or orientation / MGI
dilated heart ventricle / MGI
decreased survivor rate / MGI
thin interventricular septum / MGI
mortality/aging / MGI
neonatal lethality, complete penetrance / MGI
neonatal lethality, incomplete penetrance / MGI
prenatal lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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