RjHan:SD rat Dicer
| Status | Available to order |
| EMMA ID | EM:14765 |
| International strain name | RjHan:SD rat Dicer |
| Alternative name | rDicer |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Zygote electroporation of gene-specific gRNA and Cas9 was used to ablate regulatory region located within intron 10-11 |
| Gene/Transgene symbol | Dicer1 |
Information from provider
| Provider | Jana Kopkanova |
| Provider affiliation | Transgenic and Archiving Module, Institute of Molecular Genetics of the Czech Academy of Sciences |
| Genetic information | Dicer 1 ribonuclease III (Dicer1) gene - Mutant rats were generated by zygote electroporation of gene-specific gRNAs (5´- AGTGACATATGGCTGCTGAA-3´ and 5´- TTGAGAATCCTTCAATGTCT-3´) and Cas9 was used to ablate regulatory region located within intron 10-11. |
| Phenotypic information | Homozygous:not analyzedHeterozygous:not analyzed |
| Breeding history | 2 crossings to RjHan:SD |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | wild-type rat Sprague-Dawley , heterozygous rat Sprague-Dawley |
| Stage of embryos | 2-cell |