- increased circulating LDL cholesterol level / IMPC
- decreased hematocrit / IMPC
- increased neutrophil cell number / IMPC
- increased monocyte cell number / IMPC
- decreased leukocyte cell number / IMPC
- decreased mean corpuscular volume / IMPC
- decreased circulating triglyceride level / IMPC
- decreased hemoglobin content / IMPC
- decreased erythrocyte cell number / IMPC
- increased circulating alkaline phosphatase level / IMPC
- thrombocytopenia / IMPC
- increased lean body mass / IMPC
- decreased eosinophil cell number / IMPC
- decreased B cell number / IMPC
- decreased T cell number / IMPC
- decreased circulating serum albumin level / IMPC
- decreased circulating glucose level / IMPC
- decreased NK T cell number / IMPC
- decreased NK cell number / IMPC
- increased CD4-positive, alpha beta T cell number / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
- decreased mature B cell number / IMPC
- decreased gamma-delta T cell number / IMPC
- decreased total body fat amount / IMPC
- increased red blood cell distribution width / IMPC
- decreased circulating fructosamine level / IMPC
- decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number / IMPC
- decreased effector memory CD4-positive, alpha-beta T cell number / IMPC
- decreased effector memory CD8-positive, alpha-beta T cell number / IMPC
- decreased alpha-beta T cell number / IMPC
- increased KLRG1-positive NK cell number / IMPC
- decreased KLRG1-positive NK cell number / IMPC
C57BL/6N-Irgm1em1(IMPC)Wtsi/WtsiCnbc
Status | Available to order |
EMMA ID | EM:14780 |
International strain name | C57BL/6N-Irgm1em1(IMPC)Wtsi/WtsiCnbc |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Irgm1em1(IMPC)Wtsi |
Gene/Transgene symbol | Irgm1 |
Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
IMPC phenotypes (allele matching)
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