C57BL/6NCrl-Dkk1em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:14824
Citation informationRRID:IMSR_EM:14824 

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International strain nameC57BL/6NCrl-Dkk1em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolDkk1em1(IMPC)Ccpcz
Gene/Transgene symbolDkk1

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • absent mandible / MGI
  • microcephaly / MGI
  • abnormal forelimb morphology / MGI
  • abnormal hindlimb morphology / MGI
  • polydactyly / MGI
  • syndactyly / MGI
  • ectopic digits / MGI
  • abnormal telencephalon morphology / MGI
  • anophthalmia / MGI
  • thick apical ectodermal ridge / MGI
  • abnormal craniofacial development / MGI
  • abnormal embryonic neuroepithelium morphology / MGI
  • small interparietal bone / MGI
  • small parietal bone / MGI
  • absent nasal bone / MGI
  • absent maxilla / MGI
  • abnormal limb bud morphology / MGI
  • absent nasal placodes / MGI
  • absent optic vesicle / MGI
  • abnormal first pharyngeal arch morphology / MGI
  • abnormal mandibular prominence morphology / MGI
  • neonatal lethality, complete penetrance / MGI
  • decreased midbrain size / MGI
  • decreased forebrain size / MGI
  • rostral body truncation / MGI
  • absent frontonasal prominence / MGI
  • absent diencephalon / MGI
  • abnormal anterior head development / MGI

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

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    Legally binding conditions for the transfer

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