C57BL/6NCrl-Fras1em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:14855
Citation informationRRID:IMSR_EM:14855 

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International strain nameC57BL/6NCrl-Fras1em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolFras1em1(IMPC)Ccpcz
Gene/Transgene symbolFras1

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • abnormal rib morphology / MGI
  • abnormal sternum morphology / MGI
  • absent kidney / MGI
  • cortical renal glomerulopathies / MGI
  • abnormal kidney development / MGI
  • delayed kidney development / MGI
  • syndactyly / MGI
  • clubfoot / MGI
  • abnormal lung morphology / MGI
  • abnormal lung development / MGI
  • blistering / MGI
  • microphthalmia / MGI
  • eyelids open at birth / MGI
  • hemorrhage / MGI
  • abnormal hair growth / MGI
  • abnormal eye morphology / MGI
  • abnormal digit morphology / MGI
  • micrognathia / MGI
  • small kidney / MGI
  • no phenotypic analysis / MGI
  • single kidney / MGI
  • kidney cysts / MGI
  • abnormal lung vasculature morphology / MGI
  • abnormal basement membrane morphology / MGI
  • abnormal sternebra morphology / MGI
  • impaired branching involved in ureteric bud morphogenesis / MGI
  • cryptophthalmos / MGI
  • glomerulosclerosis / MGI
  • narrow eye opening / MGI
  • abnormal renal glomerulus morphology / MGI
  • renal/urinary system phenotype / MGI
  • craniofacial phenotype / MGI
  • abnormal ureteric bud morphology / MGI
  • abnormal lung epithelium morphology / MGI
  • bleb / MGI
  • fetal bleb / MGI
  • abnormal secondary palate development / MGI
  • preaxial polydactyly / MGI
  • abnormal palatal shelf fusion at midline / MGI
  • cleft secondary palate / MGI
  • perimembraneous ventricular septal defect / MGI
  • integument phenotype / MGI
  • fused right lung lobes / MGI
  • abnormal metanephric mesenchyme morphology / MGI
  • lethality throughout fetal growth and development, complete penetrance / MGI
  • prenatal lethality, incomplete penetrance / MGI
  • lethality throughout fetal growth and development, incomplete penetrance / MGI
  • abnormal glomerular capillary morphology / MGI
  • abnormal glomerular mesangium morphology / MGI
  • abnormal metanephros morphology / MGI
  • increased metanephric mesenchyme apoptosis / MGI
  • abnormal glomerular capsule space morphology / MGI

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Register interest

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    Practical information

    Example health report
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