IMPC phenotypes (allele matching)
C57BL/6NCrl-Il1r1em1(IMPC)Ccpcz/Ph
| Status | Under development - register interest |
| EMMA ID | EM:14858 |
| Citation information | RRID:IMSR_EM:14858 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NCrl-Il1r1em1(IMPC)Ccpcz/Ph |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Il1r1em1(IMPC)Ccpcz |
| Gene/Transgene symbol | Il1r1 |
Information from provider
| Provider | Institute of Molecular Genetics |
| Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased neutrophil cell number / MGI
- abnormal cell death / MGI
- increased body length / MGI
- increased body weight / MGI
- weight loss / MGI
- decreased anxiety-related response / MGI
- hypoactivity / MGI
- abnormal inflammatory response / MGI
- increased circulating insulin level / MGI
- no abnormal phenotype detected / MGI
- abnormal nervous system electrophysiology / MGI
- increased susceptibility to bacterial infection / MGI
- decreased immunoglobulin level / MGI
- abnormal neutrophil physiology / MGI
- enhanced wound healing / MGI
- increased growth rate / MGI
- increased liver weight / MGI
- delayed tooth eruption / MGI
- increased susceptibility to age related obesity / MGI
- decreased susceptibility to induced arthritis / MGI
- abnormal response/metabolism to endogenous compounds / MGI
- increased susceptibility to induced arthritis / MGI
- impaired febrile response / MGI
- abnormal lean body mass / MGI
- decreased susceptibility to kidney reperfusion injury / MGI
- decreased incidence of tumors by chemical induction / MGI
- increased circulating insulin-like growth factor I level / MGI
- decreased susceptibility to autoimmune diabetes / MGI
- decreased susceptibility to experimental autoimmune uveoretinitis / MGI
- abnormal vascular wound healing / MGI
- increased bone resorption / MGI
- decreased eosinophil cell number / MGI
- decreased T cell number / MGI
- sepsis / MGI
- decreased T cell proliferation / MGI
- osteomyelitis / MGI
- impaired glucose tolerance / MGI
- insulin resistance / MGI
- homeostasis/metabolism phenotype / MGI
- immune system phenotype / MGI
- abnormal food intake / MGI
- increased percent body fat/body weight / MGI
- decreased circulating creatinine level / MGI
- decreased blood urea nitrogen level / MGI
- decreased susceptibility to type IV hypersensitivity reaction / MGI
- increased circulating leptin level / MGI
- increased body mass index / MGI
- decreased tumor necrosis factor secretion / MGI
- decreased circulating interleukin-6 level / MGI
- increased circulating interleukin-18 level / MGI
- decreased circulating interleukin-18 level / MGI
- increased circulating interleukin-1 beta level / MGI
- decreased interleukin-6 secretion / MGI
- impaired neutrophil chemotaxis / MGI
- decreased transforming growth factor level / MGI
- increased gonadal fat pad weight / MGI
- increased abdominal fat pad weight / MGI
- increased inguinal fat pad weight / MGI
- increased mesenteric fat pad weight / MGI
- increased retroperitoneal fat pad weight / MGI
- enhanced contextual conditioning behavior / MGI
- increased susceptibility to bacterial infection induced morbidity/mortality / MGI
- increased total body fat amount / MGI
- abnormal circulating serum amyloid protein level / MGI
- increased respiratory quotient / MGI
- abnormal microglial cell activation / MGI
- integument phenotype / MGI
- dental pulp necrosis / MGI