C57BL/6NCrl-Nfe2l2em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:14866
Citation informationRRID:IMSR_EM:14866 

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International strain nameC57BL/6NCrl-Nfe2l2em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolNfe2l2em1(IMPC)Ccpcz
Gene/Transgene symbolNfe2l2

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • enlarged lymph nodes / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal ovary morphology / IMPC
  • decreased body weight / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal tooth morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • increased mean platelet volume / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • enlarged seminal vesicle / IMPC
  • decreased liver weight / IMPC
  • increased circulating bilirubin level / IMPC
  • increased circulating creatinine level / IMPC
  • decreased circulating glucose level / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • increased mean corpuscular hemoglobin concentration / IMPC
  • increased circulating lactate dehydrogenase level / IMPC
IMPC phenotypes (gene matching)
  • abnormal lymph node morphology / IMPC
  • abnormal ovary morphology / IMPC
  • enlarged seminal vesicle / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • increased circulating creatinine level / IMPC
  • decreased circulating glucose level / IMPC
  • abnormal skin morphology / IMPC
  • decreased liver weight / IMPC
  • abnormal thymus morphology / IMPC
  • increased mean corpuscular hemoglobin concentration / IMPC
  • increased circulating lactate dehydrogenase level / IMPC
  • increased circulating bilirubin level / IMPC
  • decreased body weight / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • enlarged thymus / IMPC
  • increased mean platelet volume / IMPC
  • abnormal tooth morphology / IMPC

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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