B6N.Cg-Acsl4tm1c(EUCOMM)Wtsi/WtsiIegBiat
| Status | Available to order |
| EMMA ID | EM:14882 |
| International strain name | B6N.Cg-Acsl4tm1c(EUCOMM)Wtsi/WtsiIegBiat |
| Alternative name | B6Brd;B6N-Tyrc-Brd Acsl4tm1c(EUCOMM)Wtsi/WtsiIeg |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Acsl4tm1c(EUCOMM)Wtsi |
| Gene/Transgene symbol | Acsl4 |
Information from provider
| Provider | Maik Dahlhoff |
| Provider affiliation | Department of Biomedical Sciences, University of Veterinary Medicine, Vienna |
| Genetic information | This line originates from EMMA strain EM:05887, B6Brd;B6N-Tyrc-Brd Acsl4tm1a(EUCOMM)Wtsi/WtsiIeg, EUCOMM ES clone EPD0066_2_D10, after breeding with a flp recombinase deleter line to convert the original tm1a targeted allele (knock-out first allele) into a tm1c conditional allele. For further details on the construction of this clone see this page at the IMPC portal: https://www.mousephenotype.org/data/alleles/MGI:1354713/tm1a(EUCOMM)Wtsi. |
| Phenotypic information | Homozygous:no phenotypeHeterozygous:no phenotype |
| Breeding history | <10 generations backcrossed to C57BL/6N; therefore, agouti pups may appear for a couple of generations. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | heterozygous C57BL/6NCrlCrlj (Crlj: Charles River Laboratories Japan) |
| Breeding at archiving centre | Mice were produced for customer (tm1c allele request). |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- X-linked non-syndromic intellectual disability / Orphanet_777