- decreased bone mineral density / IMPC
- increased leukocyte cell number / IMPC
- increased monocyte cell number / IMPC
- male infertility / IMPC
- increased mean platelet volume / IMPC
- decreased lean body mass / IMPC
- increased eosinophil cell number / IMPC
- increased B cell number / IMPC
- decreased mature B cell number / IMPC
- increased total body fat amount / IMPC
- increased red blood cell distribution width / IMPC
- decreased bone mineral content / IMPC
- increased Ly6C high monocyte number / IMPC
- increased Ly6C low monocyte number / IMPC
C57BL/6N-Herc1em3(IMPC)Wtsi/WtsiOrl
Status | Available to order |
EMMA ID | EM:15007 |
International strain name | C57BL/6N-Herc1em3(IMPC)Wtsi/WtsiOrl |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Herc1em3(IMPC)Wtsi |
Gene/Transgene symbol | Herc1 |
Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Megalencephaly-severe kyphoscoliosis-overgrowth syndrome / Orphanet_457359
IMPC phenotypes (allele matching)
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