B6;CBA-Tg(Hsp70-1-cre)1Arge/Flmg
| Status | Available to order |
| EMMA ID | EM:15068 |
| International strain name | B6;CBA-Tg(Hsp70-1-cre)1Arge/Flmg |
| Alternative name | Hs-cre1 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Hsp70-1-cre)1Arge |
| Gene/Transgene symbol | Tg(Hsp70-1-cre)1Arge |
Information from provider
| Provider | Argiris Efstratiadis |
| Provider affiliation | Biomedical Research Foundation, Academy of Athens (BRFAA) |
| Genetic information | The cre-producer mouse transgenic line Hs-cre1 expresses a cre recombinase transgene from a heat shock (Hsp70-1) gene promoter for a simple and rapid approach to ubiquitous conditional gene disruption. Hs-cre1 behaves predominantly as a 'deleter' strain, since the majority of progeny (approximately 70-85%) exhibit complete recombination, regardless of reporter locus. |
| Phenotypic information | Homozygous:NoneHeterozygous:None |
| Breeding history | Not known |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
Literature references
- Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes.;Dietrich P, Dragatsis I, Xuan S, Zeitlin S, Efstratiadis A, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;196-205; 10723724