C57BL/6NCrl-Suz12em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:15161
Citation informationRRID:IMSR_EM:15161 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Suz12em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolSuz12em1(IMPC)Ccpcz
Gene/Transgene symbolSuz12

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • increased leukocyte cell number / MGI
  • decreased cell proliferation / MGI
  • hindlimb paralysis / MGI
  • increased inferior colliculus size / MGI
  • decreased corpus callosum size / MGI
  • abnormal cerebral cortex morphology / MGI
  • abnormal stratification in cerebral cortex / MGI
  • abnormal hippocampus morphology / MGI
  • abnormal cerebellum morphology / MGI
  • increased superior colliculus size / MGI
  • abnormal posture / MGI
  • decreased embryo size / MGI
  • embryonic growth arrest / MGI
  • hydroencephaly / MGI
  • abnormal developmental patterning / MGI
  • abnormal extraembryonic tissue morphology / MGI
  • abnormal brain morphology / MGI
  • abnormal chorion morphology / MGI
  • vertebral transformation / MGI
  • spina bifida / MGI
  • abnormal embryonic neuroepithelium morphology / MGI
  • cervical vertebral transformation / MGI
  • lumbar vertebral transformation / MGI
  • thoracic vertebral transformation / MGI
  • increased lymphocyte cell number / MGI
  • abnormal amnion morphology / MGI
  • thrombocytosis / MGI
  • enlarged tectum / MGI
  • increased histiocytic sarcoma incidence / MGI
  • embryonic lethality, complete penetrance / MGI
  • embryonic lethality between somite formation and embryo turning, complete penetrance / MGI
  • embryonic lethality during organogenesis, complete penetrance / MGI
  • preweaning lethality, complete penetrance / MGI
  • abnormal amniotic cavity morphology / MGI
  • abnormal extraembryonic coelom morphology / MGI
  • abnormal ectoplacental cavity morphology / MGI
  • diastematomyelia / MGI
  • increased embryonic tissue cell apoptosis / MGI

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Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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