- increased bone mineral density / IMPC
- decreased circulating LDL cholesterol level / IMPC
- decreased circulating HDL cholesterol level / IMPC
- decreased circulating calcium level / IMPC
- abnormal head morphology / IMPC
- decreased body weight / IMPC
- decreased circulating cholesterol level / IMPC
- decreased circulating serum albumin level / IMPC
- decreased circulating total protein level / IMPC
- decreased total body fat amount / IMPC
- increased circulating fructosamine level / IMPC
- decreased circulating fructosamine level / IMPC
- preweaning lethality, incomplete penetrance / IMPC
B6Brd;B6N-Tyrc-Brd Akap9tm1a(KOMP)Wtsi/WtsiOrl
Status | Available to order |
EMMA ID | EM:15217 |
International strain name | B6Brd;B6N-Tyrc-Brd Akap9tm1a(KOMP)Wtsi/WtsiOrl |
Alternative name | EPD0033_5_D02 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Akap9tm1a(KOMP)Wtsi, |
Gene/Transgene symbol | Akap9 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from KOMP ES clone EPD0033_5_D02. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Romano-Ward syndrome / Orphanet_101016
IMPC phenotypes (allele matching)
MGI phenotypes (allele matching)
- decreased circulating LDL cholesterol level / MGI
- decreased circulating HDL cholesterol level / MGI
- decreased body weight / MGI
- abnormal tooth morphology / MGI
- increased circulating alkaline phosphatase level / MGI
- decreased lean body mass / MGI
- abnormal pelvic girdle bone morphology / MGI
- increased energy expenditure / MGI
- increased T cell number / MGI
- decreased B cell number / MGI
- decreased circulating cholesterol level / MGI
- increased oxygen consumption / MGI
- decreased circulating serum albumin level / MGI
- decreased percent body fat/body weight / MGI
- decreased circulating glucose level / MGI
- decreased circulating total protein level / MGI
- increased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- decreased mature B cell number / MGI
- increased carbon dioxide production / MGI
- decreased total body fat amount / MGI
- lethality, incomplete penetrance / MGI
- decreased circulating calcium level / MGI
- abnormal head morphology / MGI
- increased circulating fructosamine level / MGI
- decreased circulating fructosamine level / MGI
- decreased lumbar vertebrae number / MGI
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