STOCK Slc34a2tm-Nhch Tg(Vil1-cre)20Syr/Orl
Status | Available to order |
EMMA ID | EM:15297 |
International strain name | STOCK Slc34a2tm-Nhch Tg(Vil1-cre)20Syr/Orl |
Alternative name | B6N.Cg-Tg(Vil1-cre)20Syr/J (#033019) x B6;129-Slc34a2 tm1Nhch; Short name: NaPillb-villin |
Strain type | Transgenic Strains |
Allele/Transgene symbol | Cre, Promoter villin |
Gene/Transgene symbol | Cre, Promoter villin |
Information from provider
Provider | Nati Hernando |
Provider affiliation | Physiology, University Zurich |
Genetic information | Mice expressing cre recombinase under constitutive control of the mouse villin promoter, as well as two loxP sites inserted into intron 9 and exon 13 (the last one downstream the stop codon) of Slc34a2, the gene encoding the sodium/phosphate cotransporter NaPi-IIb. |
Phenotypic information | Homozygous:Increased fecal excretion of phosphate and reduced urinary excretion of phosphate.Heterozygous:No phenotype. |
Breeding history | Homozygous mice breed normally, 1 backcross to C57BL/6J. |
References | None available |
Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Animals used for archiving | heterozygous C57BL/6.129 |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Pulmonary alveolar microlithiasis / Orphanet_60025
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