B6J.Cg-Atpif1tm1-(EUCOMM)Wtsi (CD4-cre)/Cnbc
| Status | Available to order |
| EMMA ID | EM:15299 |
| International strain name | B6J.Cg-Atpif1tm1-(EUCOMM)Wtsi (CD4-cre)/Cnbc |
| Alternative name | CD4-Atp5if1-KO; Knockout of IF1 in CD4 T lymphocytes |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | loss of exon 3 in Atp5if1 in CD4+ T lymphocytes |
| Gene/Transgene symbol | Atp5if1 |
Information from provider
| Provider | José M Cuezva |
| Provider affiliation | Centro de Biología Molecular, Universidad Autónoma de Madrid |
| Genetic information | We used the Atp5if1-floxed mouse generated and described in our PLoS Biol 2021 publication (doi.org/10.1371/journal.pbio.3001252), crossed with mice expressing cre recombinase under the CD4 promoter, producing mice with deleted Atp5if1 (IF1) in CD4+ and CD8+ T lymphocytes. |
| Phenotypic information | Homozygous:None, except when stressed by infectionHeterozygous:Not studied. |
| Breeding history | 6-7 generations in C57BL/6J. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | yes |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6J |