C57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl
| Status | Under development - register interest |
| EMMA ID | EM:15448 |
| International strain name | C57BL/6NTac-Tmem94tm1c(EUCOMM)Wtsi/IcsOrl |
| Alternative name | C57BL/6NTac-Tmem94 |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Tmem94tm1c(EUCOMM)Wtsi |
| Gene/Transgene symbol | Tmem94 |
Information from provider
| Provider | Cécile FREMOND |
| Provider affiliation | CNRS-TAAM-UAR44 |
| Genetic information | This mouse line originates from EUCOMM ES clone EPD0215_1_D09. For further details on the construction of this clone see the page at ahref=https://www.mousephenotype.org/data/alleles/MGI:1919197/tm1a(EUCOMM)Wtsi target=_blankthe IMPC portal/a. Mice carrying the Tmem94tm1a(EUCOMM)Wtsi allele have been crossed to flp expressing mice (Gt(Rosa)26Sortm2(CAG-flpo,-EYFP)Ics) to obtain the Tmem94tm1c(EUCOMM)Wtsi allele. |
| Phenotypic information | Homozygous:Homozygous mice have not been generatedHeterozygous:We did not observe any significant phenotype |
| Breeding history | Rederived mice carrying the Tmem94tm1a(EUCOMM)Wtsiallele, were crossed to flp mice (Gt(Rosa)26Sortm2(CAG-flpo,-EYFP)Ics) to obtain the Tmem94tm1c(EUCOMM)Wtsi allele. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6N Tac |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- TMEM94-associated congenital heart defect-facial dysmorphism-developmental delay syndrome / Orphanet_562569