C57BL/6N-Gphnem1(IMPC)Ics/Ics

Status

Available to order

EMMA IDEM:15492
Citation informationRRID:IMSR_EM:15492 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6N-Gphnem1(IMPC)Ics/Ics
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolGphnem1(IMPC)Ics
Gene/Transgene symbolGphn

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • abnormal motor neuron morphology / MGI
  • motor neuron degeneration / MGI
  • decreased motor neuron number / MGI
  • abnormal neuromuscular synapse morphology / MGI
  • hyperresponsive / MGI
  • abnormal suckling behavior / MGI
  • abnormal posture / MGI
  • abnormal vocalization / MGI
  • apnea / MGI
  • no abnormal phenotype detected / MGI
  • abnormal nervous system electrophysiology / MGI
  • abnormal axon extension / MGI
  • abnormal retinal inner plexiform layer morphology / MGI
  • increased motor neuron number / MGI
  • neonatal lethality, complete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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