B6N(Cg)-Gt(ROSA)26Sortm5.1(CAG-cre/ERT2)Ics/Ics
Status | Available to order |
EMMA ID | EM:15548 |
International strain name | B6N(Cg)-Gt(ROSA)26Sortm5.1(CAG-cre/ERT2)Ics/Ics |
Alternative name | Gt(ROSA)26Sortm5.1(CAG-cre/ERT2)Ics |
Strain type | Targeted Mutant Strains : Knock-in |
Allele/Transgene symbol | Gt(ROSA)26Sortm5.1(CAG-cre/ERT2)Ics |
Gene/Transgene symbol | Gt(ROSA)26Sor |
Information from provider
Provider | ICS, Institut Clinique de la Souris |
Provider affiliation | ICS, Institut Clinique de la Souris |
Genetic information | This line was obtained by modification of BD10 C57BL/6N embryonic stem cells. A cre-F3-ERT2-F3 dual cassette expressed under the pCAG synthetic promoter was inserted into the Gt(ROSA)26Sor locus, by homologous recombination in ES cells. The selection cassette flanked by rox attachment sites was deleted by breeding the chimeras with a C57BL/6N dre recombinase ubiquitous deleter (MGI:6467222; EMMA strain ID EM:15557). For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:NAHeterozygous:NA |
Breeding history | The line was crossed with mice that were not fully inbred for C57BL/6N background, containing BALB/cN and 129/SvPas sequences. Expected background: BALB/cN 0.38%, C57BL/6N 98.84%, 129/SvPas 0.78%. |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
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