C57BL/6N-Fshrtm1.1(cre/ERT2)Ics/Ics
Status | Available to order |
EMMA ID | EM:15549 |
International strain name | C57BL/6N-Fshrtm1.1(cre/ERT2)Ics/Ics |
Alternative name | Fshrtm1.1(cre/ERT2)Ics |
Strain type | Targeted Mutant Strains : Knock-in |
Allele/Transgene symbol | Fshrtm1.1(cre/ERT2)Ics |
Gene/Transgene symbol | Fshr |
Information from provider
Provider | ICS, Institut Clinique de la Souris |
Provider affiliation | ICS, Institut Clinique de la Souris |
Genetic information | This line was obtained by modification of S3 C57BL/6N embryonic stem cells. An IRES-cre-F3-ERT2-F3 dual cassette was inserted into the 3' UTR region of the Fshr gene, by homologous recombination in ES cells. The selection cassette flanked by rox attachment sites was deleted by crossing the chimera with a C57BL/6N dre ubiquitous deleter (MGI:646722; EMMA strain ID EM:15557). Analysis of mRNA expression showed that the tm1.1 allele (cre probe) mRNA is expressed at an expected level in the ovaries. For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:NAHeterozygous:NA |
Breeding history | C57BL/6N inbred (3 generations). |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- 46,XX gonadal dysgenesis / Orphanet_243
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