C57BL/6NCrl-Gjb6em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:15734
Citation informationRRID:IMSR_EM:15734 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Gjb6em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolGjb6em1(IMPC)Ccpcz
Gene/Transgene symbolGjb6

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • organ of Corti degeneration / MGI
  • abnormal stria vascularis morphology / MGI
  • abnormal sebaceous gland morphology / MGI
  • enlarged sebaceous gland / MGI
  • abnormal epidermal layer morphology / MGI
  • hyperkeratosis / MGI
  • increased anxiety-related response / MGI
  • deafness / MGI
  • decreased vertical activity / MGI
  • no phenotypic analysis / MGI
  • nervous system phenotype / MGI
  • abnormal nervous system physiology / MGI
  • greasy coat / MGI
  • abnormal hair cell physiology / MGI
  • cochlear hair cell degeneration / MGI
  • abnormal stria vascularis vasculature morphology / MGI
  • cochlear inner hair cell degeneration / MGI
  • cochlear outer hair cell degeneration / MGI
  • absent endocochlear potential / MGI
  • decreased endocochlear potential / MGI
  • sensorineural hearing loss / MGI
  • abnormal blood-inner ear barrier function / MGI
  • abnormal amino acid level / MGI
  • hearing/vestibular/ear phenotype / MGI
  • immune system phenotype / MGI
  • decreased dopamine level / MGI
  • impaired hearing / MGI
  • abnormal cochlear potential / MGI
  • absent pinna reflex / MGI
  • abnormal cochlear endolymph ionic homeostasis / MGI
  • increased or absent threshold for auditory brainstem response / MGI
  • decreased threshold for auditory brainstem response / MGI
  • increased sebocyte number / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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