C57BL/6-Peds1tm1c(KOMP)Wtsi/Orl

Status

Available to order

EMMA IDEM:15845
Citation informationRRID:IMSR_EM:15845 

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International strain nameC57BL/6-Peds1tm1c(KOMP)Wtsi/Orl
Alternative nameTmem 189 tm1c
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolPeds1tm1c(KOMP)Wtsi
Gene/Transgene symbolPeds1

Information from provider

ProviderCécile FREMOND
Provider affiliationCNRS-TAAM
Genetic informationThe mouse line originates from KOMP ES clone EPD0026_4_C08. For further details on the construction of this clone see the page at the IMPC portal. Mice have been crossed with C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics to obtain the tm1c allele.
Phenotypic informationHomozygous:
Homozygous mice have not been generated

Heterozygous:
No phenotype observed
Breeding historyB6Dnk;B6Brd;B6N-Tyrc-Brd Peds1tm1a(KOMP)Wtsi/WtsiOrl (EMMA strain ID EM:13673; formerly Tmem189tm1a(KOMP)Wtsi allele) rederived mice have been crossed with C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics (EMMA strain ID EM:05490) to obtain the tm1c allele.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France
Animals used for archivingheterozygous C57BL/6NTac males

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal retina morphology / IMPC
  • increased mean platelet volume / IMPC
  • decreased lean body mass / IMPC
  • decreased circulating calcium level / IMPC
  • decreased erythrocyte cell number / IMPC
  • abnormal incisor color / IMPC
  • decreased circulating fructosamine level / IMPC
  • decreased hemoglobin content / IMPC
  • abnormal retina pigmentation / IMPC
  • decreased hematocrit / IMPC
  • decreased bone mineral density / IMPC
  • absent pinna reflex / IMPC
  • increased mean corpuscular volume / IMPC
  • abnormal eye morphology / IMPC

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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